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Dutch Lipid Clinic Network Score (DLCNS) for Familial Hypercholesterolemia (FH)
Feb 18, 2017
•
Mark Morgan
categories:
Cardiovascular
Dutch Lipid Clinic Network Score (DLCNS) for Familial Hypercholesterolemia (FH)
Part 1 - Family History
Group 1 - Each is worth 1 point, maximum possible 1 point
YES
no
<-- First degree relative with known premature coronary and/or vascular disease (men aged <55 years, women aged <60 years)
YES
no
<-- First degree relative with known LDL-cholesterol above the 95th percentile for age and gender
Group 2 - Each is worth 2 points, maximum possible 2 points
YES
no
<-- First degree relative with tendinous xanthomata and/or arcus cornealis
YES
no
<-- Children aged <18 years with LDL-cholesterol above the 95th percentile for age and gender
Part 2 - Clinical History
YES
no
<-- Patients with premature coronary artery disease (men aged <55 years, women aged <60 years) (0 to 2 points)
YES
no
<-- Patients with premature cerebral or peripheral vascular disease (men aged <55 years, women aged <60 years) (0 to 1 point)
Part 3 - Physical Examination
YES
no
<-- Tendinous xanthomata (0 to 6 points)
YES
no
<-- Arcus cornealis before 45 years of age (0 to 4 points)
Greater than 8.5 mmol per L or 330 mg per dL
6.5 to 8.4 mmol per L or 250 to 329 mg per dL
5.0 to 6.4 mmol per L or 190 to 249 mg per dL
4.0 to 4.9 mmol per L or 155 to 189 mg per dL
Less than 4.0 mmol per L or 155 mg per dL
<-- Untreated LDL Cholesterol (0 to 8 points)
Score -->
number
score=(Math.round((Q1)+(Q2)))+(2*(Math.round((Q3)+(Q4))))+(Q5)+(Q6)+(Q7)+(Q8)+(Q9)
Interpretation -->
result
score2=(Math.round((Q1)+(Q2)))+(2*(Math.round((Q3)+(Q4))))+(Q5)+(Q6)+(Q7)+(Q8)+(Q9);score2>8?'Diagnosis of Familial Hypercholesterolemia is CERTAIN':score2>5?'Diagnosis of Familial Hypercholesterolemia is PROBABLE':score2>2?'Diagnosis of Familial Hypercholesterolemia is POSSIBLE':'Diagnosis of Familial Hypercholesterolemia is UNLIKELY'
References (Hide/Show)
World Health Organization. Familial hypercholesterolemia—report of a second WHO Consultation. Geneva, Switzerland: World Health Organization; 1999
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