This is an anticoagulation decision tool.
Coumadin Adjustment Calculator This calculator guides a medical provider through adjustment of coumadin (warfarin) dosing.
1. Bleeding activity:
<--- Is bleeding present?
2. Current weekly dose:
<--- Add up all days' doses to get the current weekly dose (from 2.5 mg to 70 mg total per week)
3. INR Goal:
<--- Select the INR goal
4. Current INR:
<--- Select the current INR
5. Assessment and recommendations based on current INR zone:
INR less than 1.5. Recommended increase is 10 to 20%.12.5 mg is the minimum weekly dose threshold to make a significant dosage change for this INR zone. You may also consider manually overriding if desired (see below).
6. Pill size:
<--- Select pill size
7. Extra doses (override recommendations):
<--- Manual override: Add or subtract a 2.5 mg or 5 mg dose to new weekly total?

Adjustment selected: score interpretationscore=(((INR2to3Low1)*(WeeklyDose))+(Bleeding)+(Override));score>99999?'Life-threatening bleeding, at any INR: Hold warfarin; give prothrombin complex concentrate (or recombinant factor VIIa as an alternative) supplemented with vitamin K1 (10 mg slow IV); repeat as needed':score>9999?'Serious bleeding, at any INR: Hold warfarin; give vitamin K1 10 mg slow IV plus fresh plasma or prothrombin complex concentrate, depending on urgency; repeat vitamin K1 every 12 hours as needed':score>999?'Very high INR indicates more frequent monitoring':score>72.4?'That dosage is out of range':score>69.9?'NEW DOSE: 70 mg weekly (M 4, Tu 4, W 4, Th 4, F 4, Sa 4, Su 4)':score>67.4?'NEW DOSE: 67.5 mg weekly (M 3, Tu 4, W 4, Th 4, F 4, Sa 4, Su 4)':score>64.9?'NEW DOSE: 65 mg weekly (M 3, Tu 4, W 4, Th 4, F 3, Sa 4, Su 4)':score>62.4?'NEW DOSE: 62.5 mg weekly (M 3, Tu 4, W 3, Th 4, F 3, Sa 4, Su 4)':score>59.9?'NEW DOSE: 60 mg weekly (M 4, Tu 3, W 4, Th 3, F 4, Sa 3, Su 3)':score>57.4?'NEW DOSE: 57.5 mg weekly (M 4, Tu 3, W 3, Th 3, F 4, Sa 3, Su 3)':score>54.9?'NEW DOSE: 55 mg weekly (M 4, Tu 3, W 3, Th 3, F 3, Sa 3, Su 3)':score>52.4?'NEW DOSE: 52.5 mg weekly (M 3, Tu 3, W 3, Th 3, F 3, Sa 3, Su 3)':score>49.9?'NEW DOSE: 50 mg weekly (M 2, Tu 3, W 3, Th 3, F 3, Sa 3, Su 3)':score>47.4?'NEW DOSE: 47.5 mg weekly (M 2, Tu 3, W 3, Th 3, F 2, Sa 3, Su 3)':score>44.9?'NEW DOSE: 45 mg weekly (M 2, Tu 3, W 2, Th 3, F 2, Sa 3, Su 3)':score>42.4?'NEW DOSE: 42.5 mg weekly (M 3, Tu 2, W 3, Th 2, F 3, Sa 2, Su 2)':score>39.9?'NEW DOSE: 40 mg weekly (M 3, Tu 2, W 2, Th 2, F 3, Sa 2, Su 2)':score>37.4?'NEW DOSE: 37.5 mg weekly (M 3, Tu 2, W 2, Th 2, F 2, Sa 2, Su 2)':score>34.9?'NEW DOSE: 35 mg weekly (M 2, Tu 2, W 2, Th 2, F 2, Sa 2, Su 2)':score>32.4?'NEW DOSE: 32.5 mg weekly (M 1, Tu 2, W 2, Th 2, F 2, Sa 2, Su 2)':score>29.9?'NEW DOSE: 30 mg weekly (M 1, Tu 2, W 2, Th 2, F 1, Sa 2, Su 2)':score>27.4?'NEW DOSE: 27.5 mg weekly (M 1, Tu 2, W 1, Th 2, F 1, Sa 2, Su 2)':score>24.9?'NEW DOSE: 25 mg weekly (M 2, Tu 1, W 2, Th 1, F 2, Sa 1, Su 1)':score>22.4?'NEW DOSE: 22.5 mg weekly (M 2, Tu 1, W 1, Th 1, F 2, Sa 1, Su 1)':score>19.9?'NEW DOSE: 20 mg weekly (M 2, Tu 1, W 1, Th 1, F 1, Sa 1, Su 1)':score>17.4?'NEW DOSE: 17.5 mg weekly (M 1, Tu 1, W 1, Th 1, F 1, Sa 1, Su 1)':score>14.9?'NEW DOSE: 15 mg weekly (M 1, Tu 0, W 1, Th 1, F 1, Sa 1, Su 1)':score>12.4?'NEW DOSE: 12.5 mg weekly (M 1, Tu 0, W 1, Th 0, F 1, Sa 1, Su 1)':score>9.9?'NEW DOSE: 10 mg weekly (M 1, Tu 0, W 1, Th 0, F 1, Sa 0, Su 1)':score>7.4?'NEW DOSE: 7.5 mg weekly (M 1, Tu 0, W 1, Th 0, F 1, Sa 0, Su 0)':score>4.9?'NEW DOSE: 5 mg weekly (M 1, Tu 0, W 0, Th 0, F 1, Sa 0, Su 0)':score>2.4?'NEW DOSE: 2.5 mg weekly (M 1, Tu 0, W 0, Th 0, F 0, Sa 0, Su 0)':'That dosage is out of range!'
References (Hide/Show)
#1 Ansell (2001) Chest 119: 22S-38S.
#2 Ebell (2005) Am Fam Physician 71: 1979-82.

Result - Copy and paste this output: